Muting analog outputs quickly

I am frequently moving between using studio speakers and headphones, so use the iConfig mute buttons multiple times a day. I don't like to leave iConfig running, as it keeps my computer from going to sleep. But restarting it every time I want to mute/unmute something takes 30 seconds or so to find the interface. Is there some other quick way to control those mute options? I don't think there's a direct way to do it from the front panel without multiple presses, and that would probably be just as inconvenient as my current method.
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