Playback works but with pops and clicks (win 10, iCA4+)

Hi, I'm recording with the iConnectAudio4+ to my win 10 laptop using Reaper 64.
All fine with the recording and monitoring, however, as I playback it's full with pops, clicks, distortion and noises (same for windows system sounds or any playback from outside of reaper). How can I solve this?
Thanks alot!
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